Guideline of Alternative Animal Testing Methods (In Vitro Skin Sensitisation: human Cell Line Activation Test, h-CLAT)

Local Title

화장품 피부감작성 동물대체시험법 (인체 세포주 활성화 방법, h-CLAT) 가이드라인

Country/Region

South Korea

Competent Authority

National Institute of Food and Drug Safety Evaluation

Type

Regulation

Status

In force

Release Date

2017-09-07

Implementation Date

2017-09-07

Expert Translation

AI Translation

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Summary

Noteworthy Information

This guideline is applicable for alternative animal test method of in Vitro Skin Sensitization (human Cell Line Activation Test, h-CLAT). This test method is to assess the skin sensitization by assessing the vitalization of the dendritic cell by its expression of Cell surface marker.