As consumers' demands grow rapidly, the function of wet wipes becomes more various from the original cleansing purpose to multi-functions, such as UV-protection, make-up removal, anti-wrinkle, etc. Wet wipes of different functions are subject to different regulatory requirements. China categorizes wet wipes into hygienic and cosmetic ones which will receive respective supervisions. This Guidance tries to figure out the borderline between hygienic and cosmetic wet wipes and specify corresponding obligations that companies involved need to carry out.