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On November 12, 2021, China National Institutes for Food and Drug Control (NIFDC) opened a public consultation on a draft testing standard for cosmetic ingredient—In Vivo Mammalian Alkaline Comet Assay. Stakeholders with any comments can send them to the NIFDC via email at [email protected] before November 28, 2021.
This method specifies the basic principles, requirements, and methods of in vivo mammalian alkaline comet assay and applies to the genotoxicity test of cosmetic ingredients.
Main contents of the draft are as follows:
Scope
Normative references
Definitions
Theory
Basic principles of test
Solution preparation (all solutions are freshly used and prepared)
Test animals and breeding environment
Test conditions
Dosage design
Way of exposure
sampling time
Test methods
Results judgment method
Evaluation of test results
Test report
