On November 12, 2021, China National Institutes for Food and Drug Control (NIFDC) opened a public consultation on a draft testing standard for cosmetic ingredient—In Vivo Mammalian Alkaline Comet Assay. Stakeholders with any comments can send them to the NIFDC via email at firstname.lastname@example.org before November 28, 2021.
This method specifies the basic principles, requirements, and methods of in vivo mammalian alkaline comet assay and applies to the genotoxicity test of cosmetic ingredients.
Main contents of the draft are as follows:
Basic principles of test
Solution preparation (all solutions are freshly used and prepared)
Test animals and breeding environment
Way of exposure
Results judgment method
Evaluation of test results