Cosmetic Compliance
Intelligence & Solutions
Determination of Ethyl Acrylate and Other 39 Kinds of Components in Cosmetics (Draft for Comments)
Local Title:
化妆品中丙烯酸乙酯等40种原料的检测方法(征求意见稿)
Country/Region:
China
Competent Authority:
National Institutes for Food and Drug Control
Type:
Regulation
Status:
Draft
Release Date:
2022-07-08
Implementation Date:
/
Document
Language Source Title Access
ZH
Official Determination of Ethyl Acrylate and Other 39 Kinds of Components in Cosmetics (Draft for Comments)
On-demand Translation Service
Determination of Ethyl Acrylate and Other 39 Kinds of Components in Cosmetics (Draft for Comments)
request
Summary

On July 8, 2022, China National Institutes for Food and Drug Control (NIFDC) launched public consultation on one draft testing method for 40 fragrance components. Cosmetic stakeholders can send suggestions to hzpbwh@nifdc.org.cn before July 31, 2022.

Regarding the determination of fragrance components, China has set national standards such as "GB/T 24800.9-2009 Determination of Citral, Cinnamyl Alcohol, Anise Alcohol, Cinammal and Courmarin in Cosmetics by Gas Chromatography Method" and "GB/T 24800.10-2009 Determination of 19 Flavors in Cosmetics by Gas Chromatography-mass Spectrometry Method". However, it is found that these standards cannot fully meet the testing demand in practice, therefore this new method is developed.

This method aims to provide guidance for the identification and content determination of 40 fragrance components (see Table below) in the perfume, powder, cream, emulsion, wax-based and liquid water-based cosmetics by Gas Chromatography-mass Spectrometry (GC-MS) method. Among these 40 components, 24 are allergens specified in EU Regulation (EC) 1223/2009 (EU Cosmetics Regulation), and the other 16 are prohibited fragrance components included in Safety and Technical Standards for Cosmetics 2015 (STSC 2015) and national standard "GB/T 22731-2017 Fragrance Compound".

The Basic Information of 40 Fragrance Components:

Ref No.Ingredient NameCAS No.
1Ethyl Acrylate140-88-5
2Methyl trans-2-butenoate623-43-8
35-Methyl-2,3-hexanedione / Acetyl Isovaleryl13706-86-0
4Trans-2-heptenal18829-55-5
5Allyl Isothiocyanate57-06-7
6Dimethyl Citraconate617-54-9
7Diethyl Maleate141-05-9
8Benzyl Cyanide140-29-4
94-Phenylbut-3-en-2-one122-57-6
104-tert-Butylphenol98-54-4
11p-Hydroxyanisole150-76-5
124-ethoxyphenol622-62-8
13Musk Ambrette / 4-tert-Butyl-3-methoxy-2,6-dinitrotoluene83-66-9
14Diphenylamine122-39-4
157-Methoxycoumarin531-59-9
167-Ethoxy-4-methylcoumarin87-05-8
17d-Limonene5989-27-5
18Linalool78-70-6
19Methyl 2-octynoate111-12-6
20Citral5392-40-5
21Citronellol106-22-9
22Geraniol106-24-1
23Alpha-Isomethyl Ionone127-51-5
24Benzyl Alcohol100-51-6
25Hydroxycitronellal107-75-5
26Cinnamal104-55-2
27Butylphenyl Methylpropional80-54-6
28Eugenol97-53-0
29Amyl Cinnamal122-40-7
30Anisyl Alcohol105-13-5
31Cinnamyl Alcohol104-54-1
32Farnesol4602-84-0
33Isoeugenol97-54-1
34Hexyl Cinnamaldehyde101-86-0
35Coumarin91-64-5
364-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde  31906-04-4
37Amyl Cinnamyl Alcohol101-85-9
38Benzyl Benzoate120-51-4
39Benzyl Salicylate118-58-1
40Benzyl Cinnamate103-41-3