On July 8, 2022, China National Institutes for Food and Drug Control (NIFDC) launched public consultation on one draft testing method for 40 fragrance components. Cosmetic stakeholders can send suggestions to hzpbwh@nifdc.org.cn before July 31, 2022.
Regarding the determination of fragrance components, China has set national standards such as "GB/T 24800.9-2009 Determination of Citral, Cinnamyl Alcohol, Anise Alcohol, Cinammal and Courmarin in Cosmetics by Gas Chromatography Method" and "GB/T 24800.10-2009 Determination of 19 Flavors in Cosmetics by Gas Chromatography-mass Spectrometry Method". However, it is found that these standards cannot fully meet the testing demand in practice, therefore this new method is developed.
This method aims to provide guidance for the identification and content determination of 40 fragrance components (see Table below) in the perfume, powder, cream, emulsion, wax-based and liquid water-based cosmetics by Gas Chromatography-mass Spectrometry (GC-MS) method. Among these 40 components, 24 are allergens specified in EU Regulation (EC) 1223/2009 (EU Cosmetics Regulation), and the other 16 are prohibited fragrance components included in Safety and Technical Standards for Cosmetics 2015 (STSC 2015) and national standard "GB/T 22731-2017 Fragrance Compound".
The Basic Information of 40 Fragrance Components:
| Ref No. | Ingredient Name | CAS No. |
| 1 | Ethyl Acrylate | 140-88-5 |
| 2 | Methyl trans-2-butenoate | 623-43-8 |
| 3 | 5-Methyl-2,3-hexanedione / Acetyl Isovaleryl | 13706-86-0 |
| 4 | Trans-2-heptenal | 18829-55-5 |
| 5 | Allyl Isothiocyanate | 57-06-7 |
| 6 | Dimethyl Citraconate | 617-54-9 |
| 7 | Diethyl Maleate | 141-05-9 |
| 8 | Benzyl Cyanide | 140-29-4 |
| 9 | 4-Phenylbut-3-en-2-one | 122-57-6 |
| 10 | 4-tert-Butylphenol | 98-54-4 |
| 11 | p-Hydroxyanisole | 150-76-5 |
| 12 | 4-ethoxyphenol | 622-62-8 |
| 13 | Musk Ambrette / 4-tert-Butyl-3-methoxy-2,6-dinitrotoluene | 83-66-9 |
| 14 | Diphenylamine | 122-39-4 |
| 15 | 7-Methoxycoumarin | 531-59-9 |
| 16 | 7-Ethoxy-4-methylcoumarin | 87-05-8 |
| 17 | d-Limonene | 5989-27-5 |
| 18 | Linalool | 78-70-6 |
| 19 | Methyl 2-octynoate | 111-12-6 |
| 20 | Citral | 5392-40-5 |
| 21 | Citronellol | 106-22-9 |
| 22 | Geraniol | 106-24-1 |
| 23 | Alpha-Isomethyl Ionone | 127-51-5 |
| 24 | Benzyl Alcohol | 100-51-6 |
| 25 | Hydroxycitronellal | 107-75-5 |
| 26 | Cinnamal | 104-55-2 |
| 27 | Butylphenyl Methylpropional | 80-54-6 |
| 28 | Eugenol | 97-53-0 |
| 29 | Amyl Cinnamal | 122-40-7 |
| 30 | Anisyl Alcohol | 105-13-5 |
| 31 | Cinnamyl Alcohol | 104-54-1 |
| 32 | Farnesol | 4602-84-0 |
| 33 | Isoeugenol | 97-54-1 |
| 34 | Hexyl Cinnamaldehyde | 101-86-0 |
| 35 | Coumarin | 91-64-5 |
| 36 | 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde | 31906-04-4 |
| 37 | Amyl Cinnamyl Alcohol | 101-85-9 |
| 38 | Benzyl Benzoate | 120-51-4 |
| 39 | Benzyl Salicylate | 118-58-1 |
| 40 | Benzyl Cinnamate | 103-41-3 |
Original regulatory document
