On March 20, 2024, China National Institutes for Food and Drug Control (NIFDC) published the Technical Guidelines for Application of Threshold of Toxicological Concern (TTC) Method (the TTC Technical Guidelines) and the Technical Guidelines for Application of Read-across (the Read-across Technical Guidelines) for cosmetic safety assessment.
\With five sections and two appendices, the Read-across Technical Guidelines offers detailed instructions on employing Read Across for cosmetic safety assessment. Its content is as follows:
Overview
Scope of Application
Terms and Definition
Basic Principles
Assessment Procedures
Appendix 1 Flowchart of Safety Assessment on Cosmetics Applying Read-across
Appendix 2 Example of application of read-across method in safety assessment of cosmetic ingredients (category approach)
Original regulatory document
