In November 2022, EU notified WTO of a draft proposing to newly include 30 more CMR substances (those classified as carcinogenic, mutagenic or toxic for reproduction) into the prohibited ingredients list in Regulation (EC) No 1223/2009 (Cosmetics Regulation). On July 20, 2023, EU introduced the finalized amendments in Commission Regulation (EU) 2023/1490. The amending regulation is set to take effect on August 9, 2023, while new measures shall apply from December 1, 2023.