On June 24, 2025, China’s National Medical Products Administration (NMPA) issued a major announcement introducing substantial revisions to the Inventory of Existing Cosmetic Ingredients in China (IECIC). The update features the launch of a dual-list structure and the establishment of a dynamic adjustment mechanism, marking a new phase in China’s cosmetic ingredient supervision. The accompanying Explanation of Adjustments outlines the key changes made between IECIC 2021 and the newly released IECIC I.