This method specifies the use of high performance liquid chromatography-mass spectrometry for the qualitative and quantitative determination of 129 ingredients in cosmetics. It covers a variety of formulations, including creams, emulsions, aqueous and oil-based liquids, gels, powders, and wax-based cosmetics.

Built upon the existing standard within Safety and Technical Standards for Cosmetics, this new method expands the list of detectable ingredients from 64 to 129, and incorporates optimizations to address powder and wax-based product testing.