On March 31, 2026, the Ministry of Health, Labour and Welfare (MHLW) of Japan released an amendment to the Standards for Biological Raw Materials (MHLW Notification No. 155 of 2026). The amendment mainly revises the requirements for ruminant-derived raw materials based on international trends regarding the risk of Bovine Spongiform Encephalopathy (BSE) transmission. The revised standards took effect upon release.
Original regulatory document
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