On April 30, 2024, China's National Institutes for Food and Drug Control (NIFDC) released the finalized version of the Technical Guidelines for Application of Threshold of Toxicological Concern (TTC) Method and the Technical Guidelines for Application of Read-across Method.

The Read-across Technical Guidelines consists of five sections and two appendices, and outlines the application scope, basic principles, and evaluation procedures of Read Across, along with a flowchart and an example of its application in cosmetic safety assessments.