On May 31, 2024, the China National Institutes for Food and Drug Control (NIFDC) unveiled the Guidelines for Research and Determination of Safe Use History of New Cosmetic Ingredients (Trial) (Draft for Comments) (the Safe Use History Guidelines) and the Guidelines for Research and Determination of Safe Consumption History of New Cosmetic Ingredients (Trial) (Draft for Comments) (the Safe Consumption History Guidelines) for public consultation.

The Safe Use History Guidelines is appliable to the research and determination of the safe use history of NCIs in Situation 3 and Situation 4. It mainly outlines the overview, application scope, general principles, basic requirements for safe use history proof materials, proof material format requirements, and safety assessment requirements.