This is a Q&A document concerning the Guidelines for the Research and Determination of the Safe Use History of New Cosmetic Ingredients (Trial). The questions addressed include:

1. What is the background for developing the Guidelines for the Research and Determination of the Safe Use History of New Cosmetic Ingredients (Trial)?

2. Must the new ingredient intended for registration or notification be identical to the ingredient cited in the safe use history proof materials?

3. What are the requirements for marketed cosmetic products cited in the safe use history proof materials?

4. What are the requirements regarding the marketing date and usage amount of the referenced marketed cosmetic products?

5. How should the registrant or notifier of a new cosmetic ingredient analyze its safe usage?

6. What are the format requirements for the safe use history proof materials?