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The 34th ASEAN Cosmetic Scientific Body (ACSB) meeting was held in October 2021, during which it introduced significant changes to cosmetic ingredients in the Annexes of the ASEAN Cosmetic Directive (ACD). Detailed amendments to each Annex are as follows:
1. Add 223 prohibited ingredients in Annex II: List of Prohibited Substances
| Ref. No. | Substances | CAS. No. | Applicable Countries |
| No. A1143 | Silver Nitrate | 7761-88-8 | ASEAN Member States except Thailand |
| No. 1385-1394, No. 1401-1574, No. 1580-1641 | 222 banned substances under EU 2019/1966 and 2019/831, such as 1Hydroxylammonium nitrate, (4-Phenylbutyl) phosphinic acid, Cobalt dinitrate, Nickel dichloride, etc. Click here to see the full list. | / | ASEAN Member States except Vietnam |
| Implementation Date: 2022.10.06 | |||
2. Add eight restricted ingredients in Annex III: List of Restricted Substances
| Ref. No. ACD # (EU #) | Substance/CAS No. | Restrictions | Conditions of use and warning which must be printed on the labels | ||
| Field of application and/or use | Maximum authorised concentration in the ready for use preparation | Other limitations and requirements | |||
| 330 (315) | 4-(3 aminopyrazolo[1,5-A] pyridin-2-yl)-1,1-dimethylpiperazin-1-iumchloride hydrochloride | Hair dye substance in oxidative hair dye products | After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % (calculated as free base) Except Indonesia | To be printed on the label: The mixing ratio.  'Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary "black henna" tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary "black henna" tattoo in the past.' | |
| 331 (316) | 1-(3-((4-Aminophenyl) amino)propyl)-3-methyl- 1H-imidazol-3-ium chloride hydrochloride Methylimidazoliumpropyl p-phenylenediamine HCl | Hair dye substance in oxidative hair dye products | After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % (calculated as free base)Except Indonesia | To be printed on the label: The mixing ratio.
— you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary "black henna" tattoo in the past.' | |
| 332 (317) | Di-[2-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium]-ethyl]disulphidedimethanesulfonate HC Orange No 6 | Hair dye substance in non-oxidative hair dye products | 0.5% | Methanesulfonates impurities, in particular ethyl methanesulfonate shall not be present. Except Indonesia | |
| 333 (318) | Sodium 4-[(2-hydroxy-1-naphthyl)azo]benzene sulfonate
Acid Orange 7 633-96-5 | Hair dye substance in non-oxidative hair dye products | 0.5% | Except Indonesia | |
| 334 (319) | Phenol, 4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1- benzoxathiol-3-ylidene)bis [2,6-dibromo- | (a)Hair dye substance in oxidative hair dye products | 0.2% | After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.2 % (calculated as free base) Except Indonesia | To be printed on the label: The mixing ratio.
Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary "black henna" tattoo in the past.' |
335 | Indigofera tinctoria, dried and pulverised leaves of Indigofera tinctoria L Indigofera tinctoria leaf Indigofera tinctoria leaf powder Indigofera tinctoria leaf extract Indigofera tinctoria extract | Hair dye substance in non-oxidative hair dye products | 25% | Except Indonesia | |
| 336 (311) | Diphenyl(2,4,6- trimethylbenzoyl)phosphine oxide Trimethylbenzoyl diphenylphosphine oxide | Artificial nail systems | 5.0% | Professional use Except Indonesia | For professional use only Avoid skin contact |
| 337 (312) | 2-Furaldehyde Furfural 98-01-1 | 0.001% | Except Indonesia | ||
| Implementation Date: 2023.04.06 | |||||
3. Add a permitted preservative in Annex VI: List of Permitted Preservatives
| Ref. No. | Substance | Maximum authorized concentration | Limitations and requirements |
| 28 | Poly(1-hexamethylenebiguanide hydrochloride) Polyaminopropyl biguanide | 0.1% | Not to be used in applications that may lead to exposure of the end-user's lungs by inhalation |
| Implementation Date: 2023.04.06 | |||
4. Add a permitted UV Filter in Annex VII: List of Permitted UV Filters
| Ref. No. | Substance | Maximum authorised concentration | Other limitations and requirements |
| 31 | 2-ethoxyethyl (2Z)-2-cyano- 2-[3-(3-methoxypropylamino) cyclohex-2-en-1-ylidene]acetate Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate CAS No 1419401-88-9 | 3% | — Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation — Do not use with nitrosating agents |
| Implementation Date: Effective Immediately | |||
5. Amend requirements for three prohibited ingredients in Annex II: List of Prohibited Substances
The changes to requirements are shown in red:
| Substances | CAS Number | Ref. No. |
1,2,4-Trihydroxybenzene when used as a substance in hair and eyelash dye products Except Singapore | 533-73-3 | 1642 |
4-Amino-3-hydroxytoluene when used as a substance in hair and eyelash dye products Except Singapore | 2835-98-5 | 1643 |
2-[(4-Amino-2-nitrophenyl)-amino]-benzoic acid when used as a substance in hair and eyelash dye products Except Singapore | 117907-43-4 | 1644 |
| Implementation Date: 2022.05.28 | ||
6. Amend requirements for three restricted ingredients in Annex III: List of Restricted Substances
The changes to requirements are shown in red:
| Ref. No. ACD # (EU #) | Substance/CAS No. | Restrictions | Conditions of use and warning which must be printed on the labels | ||
| Field of application and/or use | Maximum authorised concentration in the ready for use preparation | Other limitations and requirements | |||
| 13 | Formaldehyde | Nail hardening products | 2.2% calculated as formaldehyde | Allowed only in Lao PDR, Thailand and Vietnam | Protects cuticles with grease or oil. |
| 328 (313) | 2-Hydroxyethyl Methacrylate HEMA | Nail Products | Professional use only | For professional use only | |
| 329 (315) | 11,14-Dioxa-2,9- diazaheptadec-16-enoic Acid, 4,4,6,16- tetramethyl-10,15- dioxo, 2-[(2-methyl- 1-oxo-2-propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE | Nail Products | Professional use only | For professional use only | |
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