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On May 7, 2025, China National Medical Products Administration (NMPA) announced amendments to the Safety and Technical Standards for Cosmetics (2015 Edition) (STSC), introducing 5 new testing methods and revising 2 existing testing methods. 1 These methods will take effect on March 1, 2026, and will apply to cosmetic registration, notification, and sampling testing. Prior to their implementation, NMPA encourages the use of these updated methods for related testing.
No. | Testing Methods | Type | Range of Application | Chapter of the New/Revised Testing Methods in STSC |
1 | Determination of Hard Particles in Toothpaste | New physical and chemical testing methods | It is applicable to the determination of hard particles in toothpaste. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
1 General Principles of Physical and Chemical Testing Methods
1.17 Determination of Hard Particles in Toothpaste |
2 | Determination of Diethylene Glycol and Glycol in Toothpaste | It is applicable to the determination of diethylene glycol and ethylene glycol in toothpaste, using gas chromatography method. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
2 Testing Methods of Prohibited Ingredients
2.40 Determination of Diethylene Glycol and Glycol in Toothpaste | |
3 | Determination of Soluble/Free Fluoride in Toothpastes | It is applicable to the determination of soluble/free fluoride in toothpastes, using fluoride ion-selective electrode method. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
3 Testing Methods of Restricted Ingredients
3.15 Determination of Soluble/Free Fluoride in Toothpastes | |
4 | Determination of Total Fluoride in Toothpaste | It is applicable to the determination of total fluoride in toothpaste, using gas chromatography method. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
3 Testing Methods of Restricted Ingredients
3.16 Determination of Total Fluoride in Toothpaste | |
5 | In Chemico Skin Sensitisation The ARE-Nrf2 Luciferase LuSens Test | New toxicological testing method | It specifies the basic principles, test methods and technical requirements of the in vitro skin sensitisation ARE-Nrf2 luciferase LuSens test. It is applicable to the assessment of the skin sensitisation potential of chemical ingredients for cosmetics. | Chapter 6 Toxicological Testing Methods for Cosmetics
44 In Chemico Skin Sensitisation The ARE-Nrf2 Luciferase LuSens Test |
6 | Determination of Li and 42 Kinds of Elements in Cosmetics | Revised physical and chemical testing methods | It is applicable to the determination of Li and 42 kinds of elements in cosmetics, using inductively coupled plasma mass spectrometry (ICP-MS) method. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
1 General Principles of Physical and Chemical Testing Methods
1.6 Determination of Li and 42 Kinds of Elements in Cosmetics |
7 | Determination of Li and 42 Kinds of Elements in Toothpaste | It is applicable to the determination of Li and 42 kinds of elements in toothpaste, using inductively coupled plasma mass spectrometry (ICP-MS) method. | Chapter 4 Physical and Chemical Testing Methods for Cosmetics
1 General Principles of Physical and Chemical Testing Methods
1.16 Determination of Li and 42 Kinds of Elements in Toothpaste |
For the detection limits of hard particles, diethylene glycol, glycol, total fluorine, soluble fluorine, and free fluorine in toothpaste, please refer to Annex 3 "Microbiological and Physical and Chemical Testing Items for Toothpaste Notification" of Provisions for Management of Toothpaste Notification Dossiers.
With extensive experience in toothpaste notification, ChemLinked’s parent company REACH24H Consulting Group offers compliance solutions to assist overseas cosmetic enterprises entering into China market. Welcome to contact us at [email protected] for more advice.
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