Japan Released Cosmetic Skin Sensitization Test Alternative Method Guidelines

Takehome:

Japan released a guideline detailing in vitro alternative methods for cosmetic skin sensitization testing.

In order to promote the use of skin sensitization test alternative methods (in vitro tests) for safety evaluation of quasi-drugs and cosmetics, Japan MHLW provide a guideline to explain examples and operations of these alternative methods. The implementation of these alternative methods follows international standards. In this guideline, each method's principle, test flow, test conditions, judgment are outlined. ChemLinked uploaded the original document of "Guidelines of Cosmetic Skin Sensitization Test Alternative Methods" to the database, you may refer to it.