[Updated] Taiwan Amends the List of Prohibited Ingredients in Cosmetics

Editor's note: This article was originally published on December 14, 2023, and was updated on March 22, 2024, as per the latest developments. The updated contents are marked in red below.

On December 13, 2023, Taiwan Food and Drug Administration (TFDA) introduced draft amendments to the List of Prohibited Ingredients in Cosmetics.¹ These amendments were finalized on March 21, 2024, and the majority of them are set to take effect on January 1, 2025.²

Compared to the current list, the amended version newly includes nine ingredients. These ingredients have already been banned for use in cosmetic products in ASEAN and EU. To align with international regulations on them, TFDA introduces their prohibition. Additionally, TFDA revises the use conditions of two existing ingredients, details of which can be found in the table below. According to TFDA, the revisions to the substances listed under reference number 11 became effective on March 21, 2024. All other amendments, except for this, will come into force on January 1, 2025.

Status	Substance	CAS No.	Ref. No.
Addition	Aminocaproic acid (INN) and its salts	60-32-2	651
	3-and 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde / HICC	51414-25-6 / 31906-04-4	652
	2,6-Dihydroxy-4-methyl-benzaldehyde / atranol	526-37-4	653
	3-Chloro-2,6-Dihydroxy-4-methylbenzaldehyde / chloroatranol	57074-21-2	654
	Perfluorooctane sulfonic acid / heptadecafluorooctane-1-sulfonic acid [1] Potassium perfluorooctanesulfonate / potassium heptadecafluorooctane-1-sulfonate [2] Diethanolamine perfluorooctane sulfonate [3] Ammonium perfluorooctane sulfonate / ammonium heptadecafluorooctanesulfonate [4] Lithium perfluorooctane sulfonate / lithium heptadecafluorooctanesulfonate [5]	1763-23-1 [1] 2795-39-3 [2] 70225-14-8 [3] 29081-56-9 [4] 29457-72-5 [5]	655
	Ammonium pentadecafluorooctanoate	3825-26-1	656
	Perfluorooctanoic acid	335-67-1	657
	Nonadecafluorodecanoic acid [1] Ammonium nonadecafluorodecanoate [2] Sodium nonadecafluorodecanoate [3]	335-76-2 [1] 3108-42-7 [2] 3830-45-3 [3]	658
	Perfluorononan-1-oic acid [1] and its sodium [2] and ammonium [3] salts	375-95-1 [1] 21049-39-8 [2] 4149-60-4 [3]	659
Revision	Cells, tissues or products of human origin, except for specific exosomes-related cases* that have been reviewed and approved by the competent authority	/	11
Revision	Zirconium and its compounds, except for zirconium lakes, salts, or pigments used as colouring agents, and substances otherwise specified in the restricted ingredients list	7440-67-7	60
Notes: * Effective from March 21, 2024³, for case review, the applicant should submit relevant documents or information, including the qualifications of the exosome donor, preparation processes and inspection reports, stability tests, safety tests, as well as absorption, distribution, metabolism, and excretion tests.

[Updated] Taiwan Amends the List of Prohibited Ingredients in Cosmetics

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