CFDA Approve Two More Animal Testing Methods

  •   24 Aug 2017
  •    Jo Zhou


    CFDA just approved two more testing methods for cosmetics —— In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER) and Skin Photoallergy Test.

    These two methods still involve animal testing. The testing methods will be used for cosmetic toxicological assessment and will be designated as test No.19 and No.20 in the “Cosmetic Safety and Technical Standard”. The Transcutaneous Electrical Resistance Test(TER)is to evaluate if chemical ingredients in cosmetics are corrosive to mammalian skin and the Skin Photoallergy Test is to check if repeated use of a cosmetic will cause photoallergy.

    REACH24H Interpretation:

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    Please see the definitions of animal testing. 3T3 and TER both could be treated alternative to animal testing. Animal testing usually refers to any experiments using living animals, rather than dead animal. Therefore, the title of this article is not right!
    True, Alternative to animal testing are very clearly defined in REACH guidelines and Many are still in pipeline of ECVAM; which are yet to be validated to support Alternative to animal testing regime . With authentic validation and wider applicable range, in-vitro methods can establish a strong scientific hold to provide a alternative to animal models . The efforts from EU and ECHA are commendable with advances in Alternative to animal models. Dr. Vimarsh +91 9743833808 BD - GLP Agrochemicals
    Thank you for your comment. We understand the "definition of animal testing" you mean, but in the document, it stated the tested animal---rats should be collected lively and killed for in vitro testing. According to 9th edition of SCCS, it describe alternatives for animal testing as "The SCCS would like to stress that currently available in vitro methods only constitute a fraction of the alternative methodology meant by Russell et al. (1959), proposing the ultimate alternative methodology, namely replacement of the laboratory animal by non sentient material (organs, tissue sections, cell cultures, …). Nevertheless, although replacement remains the ultimate goal, reduction of the number of animals and refinement of the methodology by reducing the pain and distress of the animals provide realistic and significant improvements of actual testing methods and strategies (see also Section 3-4)." So we discussed with internal expert, the TER is hard to be defined purely as alternative for animal tesing. If it caused your confusion, we may discuss about this and figure out a better definition for this new method. Regards.