China Cosmetic Safety and Technical Standards Includes a New Determination Method of 22 Sunscreens in Cosmetics

As revealed by No.2019-40 Notice of China National Medical Products Administration (NMPA) on July 11 ^[1], a new sunscreens testing method has been newly included into the chapter 4 “Physical and Chemical Testing Methods for Cosmetics” of Cosmetics Safety and Technical Standards, bringing the total number of sunscreens testing methods to 8.

(Cosmetics Safety and Technical Standards 4: 5)

The Method-Determination of 3-benzylidene camphor and other 21 kinds of sunscreens in cosmetics-uses HPLC to determine the content of 3-benzylidene camphor and other 21 kinds of sunscreens in cosmetics such as liquid water-based cosmetics, cream, lotion and nail polish.

The 22 sunscreens are as follows:

No.	English Name	INCI Name	CAS No.
1	3-Benzylidene camphor	3-Benzylidene camphor	15087-24-8
2	3-(4’-Methylbenzylidene)-dl- camphor	4-Methylbenzylidene camphor	36861-47-9
3	Oxybenzone (INN)	Benzophenone-3	131-57-7
4	2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt	Benzophenone-4	4065-45-6
4		Benzophenone-5	6628-37-1
5	Alpha-(2-oxoborn-3-ylidene)-toluene-4-sulfonic acid and its salts	-	56039-58-8
6	2,2’-(6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl)bis(5-((2-ethylhexyl)oxy)phenol)	Bis-ethylhexyloxyphenol methoxyphenyl triazine	187393-00-6
7	1-(4-Tert-butylphenyl)-3-(4-methoxyphenyl) propane-1,3-dione	Butyl methoxydibenzoylmethane	70356-09-1
8	N,N,N-trimethyl-4-(2-oxoborn-3-ylidene methyl) anilinium methyl sulfate	Camphor benzalkonium methosulfate	52793-97-2
9	Benzoic acid, 2-(4-(diethylamino) -2-hydroxybenzoyl) -,hexyl ester	Diethylamino hydroxybenzoy hexyl benzoate	302776-68-7
10	Benzoic acid, 4,4’-((6-(((((1,1-dimethylethyl) amino) carbonyl)phenyl)amino) 1,3,5-triazine-2,4-diyl)diimino)bis-, bis-(2-ethylhexyl) ester	Diethylhexyl butamido triazone	154702-15-5
11	Disodium salt of 2,2’-bis-(1,4-phenylene)1H-benzimidazole-4,6-disulfonic acid	Disodium phenyl dibenzimidazole tetrasulfonate	180898-37-7
12	Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-(trimethylsilyl)oxy)-disiloxanyl)propyl	Drometrizole trisiloxane	155633-54-8
13	4-Dimethyl amino benzoate of ethyl-2-hexyl	Ethylhexyl dimethyl PABA	21245-02-3
14	2-Ethylhexyl 4-methoxycinnamate	Ethylhexyl methoxycinnamate	5466-77-3
15	2-Ethylhexyl salicylate	Ethylhexyl salicylate	118-60-5
16	2,4,6-Trianilino-(p-carbo-2’-ethylhexyl-l ’-oxy)-1,3,5-triazine	Ethylhexyl triazone	88122-99-0
17	Homosalate (INN)	Homosalate	118-56-9
18	Isopentyl-4-methoxycinnamate	Isoamyl p-methoxycinnamate	71617-10-2
19	2,2’-Methylene-bis(6-(2H-benzotriazol2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol)	Methylene bis-benzotriazolyl tetramethylbutylphenol	103597-45-1
20	2-Cyano-3,3-diphenyl acrylic acid, 2-ethylhexyl ester	Octocrylene	6197-30-4
21	2-Phenylbenzimidazole-5-sulfonic acid and its potassium, sodium, and triethanolamine salts	-	27503-81-7
22	3,3’-(1,4-Phenylenedimethylene)bis(7,7- dimethyl-2-oxobicyclo-[2.2.1]hept-1-ylmethanesulfonic acid) and its salts	-	90457-82-2

ChemLinked has collected and sorted out the concentration requirements of the above-mentioned sunscreens in cosmetics, please refer to the Cosme-list for the detail.