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As revealed by the No. 2019-12 Notice of China NMPA on March 22, 9 testing methods including 5 new methods and 4 revised methods will be included in the Safety and Technical Standards for Cosmetics.
As of January 1, 2020, the relevant testing of cosmetic registration, filing and supervision and inspection shall adopt these nine testing methods.
Detailed information of the nine testing methods are listed below:
| No. | Types | Newly-added/Amended Entries | Name of Testing Method | Notes |
| 1 | Newly-added testing methods | Chapter 4 Physical and Chemical Testing Methods for Cosmetics 4. Testing Methods of Preservatives | Determination of free formaldehyde in cosmetics | This method applies to the determination of free formaldehyde content in water, cream and lotion, gel cosmetics. |
| 2 | Chapter 6 Methods of Toxicological Test, 21 Short Time Exposure In Vitro Test Method (STE) | Short Time Exposure In Vitro Test Method (STE) | This method applies to the determination of eye irritation of chemical raw materials for cosmetics. | |
| 3 | Chapter 6, 22 Skin Sensitization: Local Lymph Node Assay: DA（LLNA: DA） | Skin Sensitization: Local Lymph Node Assay: DA（LLNA: DA） | This method applies to the determination of skin sensitization of chemical raw materials for cosmetics. | |
| 4 | Chapter 6, 23 Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA（LLNA: BrdU-ELISA） | Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA（LLNA: BrdU-ELISA） | This method applies to the determination of skin sensitization of chemical raw materials for cosmetics. | |
| 5 | Chapter 6, 24 In Chemico Skin Sensitization: Direct Peptide Reactivity Assay (DPRA) | In Chemico Skin Sensitization: Direct Peptide Reactivity Assay (DPRA) | This method applies to the evaluation of potential skin sensitization of a single component (a quantitatively composed substance with at least 80% (W/W) of one of the major components) or a multicomponent (a quantitatively composed substance, the content of more than one component is greater than or equal to 10%, and less than 80%) cosmetic ingredients. | |
| 6 | Amended testing methods | Chapter 4, 2. Testing Methods of Prohibited Ingredients | Determination of Cantharidin and Chlormethine in Cosmetics | This method applies to the determination of chlormethine and cantharidin content in liquid, cream and lotion cosmetics. |
| 7 | Chapter 4, 3. Testing Methods of Restricted Ingredients | Determination of 10 α-hydroxy acid in cosmetics |
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| 8 | Chapter 6, 8 Salmonella Typhimurium/Reverse Mutation Assay | Bacterial Reverse Mutation Assay | The specification applies to the detection of gene mutation for cosmetic raw materials and products. | |
| 9 | Chapter 6, 16 Teratogenicity Test | Teratogenicity Test | This specification applies to the detection of teratogenic cosmetic raw materials. |
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