Request a DemoIn China, cosmetic ingredients are categorized as new cosmetic ingredients and existing cosmetic ingredients. Existing cosmetic ingredients refer to ingredients included in the Inventory of Existing Cosmetic Ingredients in China (IECIC), a comprehensive reference that includes all ingredients used in cosmetics produced and sold in China. Ingredients not on this list are considered new cosmetic ingredients (NCIs). Companies intending to introduce newingredients into their products shall undergo a pre-market registration or notification process.
Before the implementation of the Cosmetic Supervision and Administration Regulation (CSAR) in 2021, obtaining approval for NCI can be challenging. From 1990 to 2020, there are only 14 new cosmetic ingredients were approved. However, the introduction of CSAR has significantly transformed this situation. Since May 1, 2021, China has adopted a risk-based classification system, managed by the National Medical Products Administration (NMPA), to regulate NCIs. This new system has facilitated the approval of nearly 200 new ingredients, marking a substantial increase in new ingredient notifications. This shift also highlights the growing significance of ingredient innovation for beauty companies to maintain a competitive edge.
Part 1 Regulatory Framework and Competent Authority
1. Main Regulations for NCI in China
| Regulations | Notes | Effective Date | Status |
| Cosmetic Supervision and Administration Regulation (CSAR) | CSAR is the overarching cosmetic regulation in China. It is designed to address issues revolving around cosmetic pre-market and post-market regulation, including the new ingredient management. | 2021-01-01 | In force |
| Administrative Measures on Cosmetics Registration and Notification (Chapter II) | Chapter II of this regulation outlines the procedures for registering and notifying new cosmetic ingredients, as well as the requirements for their safety monitoring and reporting. | 2021-05-01 | In force |
| Provisions for Management of New Cosmetic Ingredient Registration and Notification Dossiers | These provisions detail the necessary dossiers when applying for registration or notification of NCI. | 2021-05-01 | In force |
| Guidelines for the Approval of Registration of Cosmetics and New Cosmetic Ingredients | Released by China National Institutes for Food and Drug Control (NIFDC), the guideline provides clear details and time limits for the first registration, registration change, registration renewal, and registration cancellation applications of high-risk NCIs. | 2023-06-05 | In force |
| Answers for Questions about New Cosmetic Ingredient Registration and Notification Management | The NMPA answered frequently asked questions about NCI registration and notification, aimed at helping cosmetics companies gain a deeper understanding of NCIs. | 2021-11-11 | In force |
| Administrative Measures on Toothpaste | New toothpaste ingredients with preservative or coloring efficacy shall be registered with NMPA. Other new toothpaste ingredients shall be subject to notification. | 2023-12-01 | In force |
| Safety and Technical Standards for Cosmetics 2015 | The physical and chemical testing, microbiological testing, human trial safety testing, efficacy evaluation as well as toxicological testing of NCI shall be in line with the testing methods prescribed in the Safety and Technical Standards for Cosmetics (STSC). | 2016-12-01 | In force |
2. Competent Authority
NMPA is established under the governance of the State Administrative for Market Regulation (SAMR) to take all the work of the former CFDA. NMPA is tasked with developing and enforcing regulatory policies and standards for cosmetics, including overseeing NCIs to comply with related regulations and standards. This involves managing the registration and notification processes and monitoring the market to ensure their safe and effective use, thereby safeguarding consumer health.
Part 2 Definition and Classification of NCI
1. Definition
Cosmetic ingredients not listed in IECIC are considered NCIs. According to Article 11 of CSAR, a new cosmetic ingredient refers to a natural or artificial ingredient applied to cosmetic products for the first time in China. Such an ingredient must obtain approval from the NMPA before it can be used in cosmetics. After a three-year monitoring period, it will be included in the IECIC. Until then, it will remain regulated as a new cosmetic ingredient.
It should be noted that only when the application method, application area, and the intended purpose of the ingredient meet the attributes of cosmetics, can it be registered or notified as an NCI. The following two kinds of ingredients cannot be registered or notified as NCIs:
The ingredient efficacy needs to be achieved orally or by injection. The application method is not aligned with the definition of cosmetics use (spreading, spraying, or other similar methods).
Ingredient whose application area or intended purpose falls outside the definition of cosmetics—cosmetics should be applied on the external part of human body (such as skin, hair, or lip) for cleansing, protecting, beautifying, or grooming purposes.
2. Classification
Starting from May 1, 2021, China has adopted a risk-based classification system for new cosmetic ingredients with corresponding regulatory requirements.
Classification | Specifics | Approval Types |
High-risk NCI | Preservatives UV filters Colorants Hair dyes Freckle removal or whitening agents | Registration |
Relative high-risk NCI | Anti-hair loss Anti-acne Anti-wrinkle (except physical anti-wrinkle) Anti-dandruff Deodorant | Notification |
Low-risk NCI | All NCIs except for the high-risk NCI | Notification |
High-risk NCIs require comprehensive registration and approval from the NMPA, including format review and technical review. Relative high-risk and Low-risk NCIs are subject to a less rigorous regulatory framework. Instead of requiring registration and approval, these ingredients are subject to notification.
Part 3 Notification and Registration of NCI
Cosmetic companies seeking to use NCIs or cosmetic ingredient companies intending to export NCIs to China must go through registration or notification, depending on the risk classification of the ingredient.
1. Application Process
For overseas companies, they shall authorize a Chinese enterprise as the Responsible Person (RP). The RP plays a crucial role in facilitating the application process. Responsibilities of the RP include applying for an application account, arranging NCI testing, and preparing application dossiers.
When applying for high-risk ingredients, the registrant shall submit the required documents to the NMPA. The NMPA will complete a format review within 5 working days. If the documents are complete and meet relevant requirements, they will be forwarded for technical review, which will be completed within 90 working days. After approval, a registration certificate will be issued, and the information will be made public within 5 working days. The entire registration process takes a maximum of 128 working days.
For the notification process of relatively high and low-risk ingredients, companies shall submit the dossiers online to have their ingredients considered as “notified” and eligible for manufacture or import. The basic notification information will be made public within 5 working days after the submission. This streamlined approach enhances notification efficiency and enables NCIs to reach the market more quickly.
2. Dossiers Necessary for Notification and Registration
On July 8, 2024, NMPA announced the full implementation of the electronic submission for NCI registration and notification materials. Starting from September 1, 2024, all Chinese domestic registrants, notifiers, responsible persons, and cosmetics manufacturers will be required to submit registration and notification materials for NCIs through the online platform Cosmetics Registration and Notification Information Service. Paper submissions will no longer be required but domestic entities should archive the relevant paper documents.
The required notification dossiers for account application and NCI registration¬ification are detailed below.
Type | Dossiers |
Account Application |
|
NCI Registration & Notification |
i. R&D background of the ingredients ii. Basic information of the ingredients iii. Use information on the ingredients iv. Documents on functional basis v. Other documents related to the R&D of new ingredients
i. Brief description of the preparation techniques ii. Stability test data iii. Quality specification indicators and testing methods
i. Toxicological safety assessment documents ii. Safety risk assessment documents
|
3. Safety Monitoring and Reporting
According to the Administrative Measures on Cosmetics Registration and Notification, new cosmetic ingredients that have been registered or notified are subject to a safety monitoring system. The safety monitoring period is 3 years, starting from the date when the cosmetics containing the new ingredient are registered or notified for the first time.
During this monitoring period, registrants and notifiers must submit annual reports on the use and safety data of the new ingredient to the NMPA and may be required to perform safety assessments. If safety concerns arise with any new cosmetic ingredients, their registration or notification may be revoked. Ingredients that demonstrate no safety issues after three years will be included in the IECIC.
4. Safety Re-assessment
For the NCIs that have already been included in the IECIC, registrants or notifiers may be required to take additional assessments if there is a new recognition of its safety or evidence showing that the NCI may have any safety risks. If the re-assessment confirms that the NCI poses safety risks, the NCI will be prohibited from use or subject to a use restriction.
Part 4 Details of Notified New Cosmetic Ingredients
Detailed information on newly registered cosmetic ingredients can be found in the NMPA data query system. The table below displays the key details of NCIs that have been notified since the implementation of the CSAR. This table will be regularly updated with the latest information. Please stay tuned for the most current information on NCIs in China.
| No. | INCI | CAS No. | Purpose of use | Applicable scope | The Maximum Concentration | Notified Date | Notified Company |
| 175 | β-Nicotinamide Mononucleotide | / | Technical requirements have not been made public | 2024/8/13 | Zein Biotechnology Co., Ltd | ||
| 174 | Pterostilbene | / | Technical requirements have not been made public | 2024/8/6 | Guangzhou Qingnong Biotechnology Co., Ltd | ||
| 173 | Pyrroloquinoline quinone disodium salt | / | Technical requirements have not been made public | 2024/8/1 | Hubei Magic Health Technology Co.,Ltd. | ||
| 172 | Lactobacillus/Coffea arabica seed fermentation filtrate | / | Technical requirements have not been made public | 2024/7/30 | Shenzhen Hujia Technology Co., Ltd. | ||
| 171 | METAPANAX DELAVAYI extract | / | Technical requirements have not been made public | 2024/7/30 | Yunnan Botanee Group | ||
| 170 | ANOECTOCHILUS ROXBURGHII extract | / | Technical requirements have not been made public | 2024/7/22 | Guangzhou Yuanxiang Biotechnology Co., Ltd. | ||
| 169 | 10-Hydroxy-2-decenoic acid | / | Technical requirements have not been made public | 2024/7/19 | Shandong Freda Biological Co., Ltd. | ||
| 168 | Matrine Salicylate | / | Technical requirements have not been made public | 2024/7/19 | Harbin Voolga Technology Co., Ltd | ||
| 167 | Pterostilbene | / | Technical requirements have not been made public | 2024/7/18 | Zhuhai BERI PHARMA CO., LTD. | ||
| 166 | Tectorigenin | / | Technical requirements have not been made public | 2024/7/17 | Shanghai Cheermore Industrial Development Co., Ltd. | ||
| 165 | Isopropyl glycerin | / | Technical requirements have not been made public | 2024/7/9 | Solvay (Shanghai) International Trading Co., Ltd. | ||
| 164 | Sessile Ganoderma mycelium fermentation product filtrate | / | Technical requirements have not been made public | 2024/7/9 | Hunan Shuiyang Biotechnology Co., Ltd. | ||
| 163 | Fucosyllactose | / | Technical requirements have not been made public | 2024/6/27 | Suzhou Yixi Biotech Co., Ltd | ||
| 162 | Vitamin K2 | / | Technical requirements have not been made public | 2024/6/25 | Guangdong Sungen Bioscience Co.,Ltd. | ||
| 161 | MECONOPSIS RACEMOSA EXTRACT | / | Technical requirements have not been made public | 2024/6/24 | Yunnan Botanee Group | ||
| 160 | Cyclotetrapeptide-24 aminocyclohexane carboxylate | / | Technical requirements have not been made public | 2024/6/18 | Shenzhen Winkey Technology Co., Ltd | ||
| 159 | Hydroxyectoine | / | Technical requirements have not been made public | 2024/6/18 | Zhejiang Harre Nature Biotechnology Co., Ltd. | ||
| 158 | Bakuchiol | / | Technical requirements have not been made public | 2024/6/14 | Shenzhen Winkey Technology Co., Ltd | ||
| 157 | NAEMATELIA AURANTIALBA FRUITING BODY EXTRACT | / | Technical requirements have not been made public | 2024/6/12 | Guangzhou Jiachuang Biotechnology Co., Ltd. | ||
| 156 | Dihydroquercetin | / | Technical requirements have not been made public | 2024/6/4 | Guangdong Bawei Biotechnology Co., Ltd. | ||
| 155 | Glyceryl Hydroxybutyrate | / | Technical requirements have not been made public | 2024/6/3 | Zhejiang Harre Nature Biotechnology Co., Ltd. | ||
| 154 | GLYCINE TOMENTELLA ROOT EXTRACT | / | Technical requirements have not been made public | 2024/5/24 | MORITA BIOTECH CO., LTD. | ||
| 153 | IDESIA POLYCARPA FRUIT/SEED OIL | / | Technical requirements have not been made public | 2024/5/17 | Zhonglin Oil Technology Co., Ltd. | ||
| 152 | AMPS/HEMA Crosspolymer | / | Technical requirements have not been made public | 2024/5/17 | Scott Bader (Shanghai) Trading Co., Ltd. | ||
| 151 | Calixarene 8A-12C | / | Technical requirements have not been made public | 2024/5/14 | Suzhou Junde Biotechnology Co., Ltd. | ||
| 150 | RGD Amidated Hyaluronic Acid | / | Technical requirements have not been made public | 2024/5/14 | Shaanxi Biohong Synthetic Biotechnology Co., Ltd. | ||
| 149 | Soybean Oil Glycerides/Octyldodecyl Maleate | / | Technical requirements have not been made public | 2024/5/10 | Ashland Inc. | ||
| 148 | ANOECTOCHILUS ROXBURGHII EXTRACT | / | Technical requirements have not been made public | 2024/5/9 | Fujian PienTzeHuang Cosmetics Co., Ltd. | ||
| 147 | Acetyl Dipeptide-1 | / | Technical requirements have not been made public | 2024/5/7 | Shandong Jitai Biotech Co., Ltd. | ||
| 146 | Donkey Milk Powder | / | Technical requirements have not been made public | 2024/4/26 | Sangyang Biotechnology (Beijing) Co., Ltd. | ||
| 145 | Bis-(phenylazotoluidine) bis-(triethoxysilylpropylcarbamoylPEG-5/PPG-5ethanol)sulfone | / | Technical requirements have not been made public | 2024/4/16 | Intercos S.p.A. | ||
| 144 | Methylbenzothiazole Azotoluidine Bis-(TriethoxysilylpropylcarbamoylPEG-5/PPG-5 Ethanol) | / | Technical requirements have not been made public | 2024/4/16 | Intercos S.p.A. | ||
| 143 | CYCLOHEXAPEPTIDE-9 | / | Technical requirements have not been made public | 2024/4/7 | Shanghai Zhongyi Daily Chemical Co., Ltd. | ||
| 142 | LEDUM PALUSTRE LEAF OIL | / | Technical requirements have not been made public | 2024/4/7 | Inner Mongolia Daxinganling Forest Products Co., Ltd. | ||
| 141 | HORDEUM VULGARE VAR. COELESTE SEED EXTRACT | / | Technical requirements have not been made public | 2024/4/7 | Nutri-Woods Bio-tech (Beijing) Co., Ltd. | ||
| 140 | Sorbeth-230 Tetraoleate | / | Technical requirements have not been made public | 2024/3/21 | Applechem, Inc. | ||
| 139 | Polyacrylate Crosspolymer-11 | / | Technical requirements have not been made public | 2024/3/21 | Clariant International Ltd. | ||
| 138 | CAESALPINIA SPINOSA GUM/AMMONIUM AMPS CROSSPOLYMER | / | Technical requirements have not been made public | 2024/3/18 | Clariant International Ltd. | ||
| 137 | Bakuchiol | / | Technical requirements have not been made public | 2024/3/14 | Guangdong Yuewei Biotechnology Co., Ltd. | ||
| 136 | TAXUS WALLICHIANA MAIREI TWIG EXTRACT | / | Technical requirements have not been made public | 2024/3/8 | Yunnan Botanee Biotechnology Group Co., Ltd | ||
| 135 | TAXUS WALLICHIANA MAIREI SEED OIL | / | Technical requirements have not been made public | 2024/3/8 | Yunnan Botanee Biotechnology Group Co., Ltd | ||
| 134 | Gelatin Crosspolymer | / | Technical requirements have not been made public | 2024/3/1 | Shenzhen Huanova Biotechnology Co., Ltd. | ||
| 133 | Tri(polyglyceryl-3/lauryl) Hydrogenated Trilinoleate | / | Technical requirements have not been made public | 2024/2/22 | CRODA Chemicals (Shanghai) Co., Ltd. | ||
| 132 | COREOPSIS TINCTORIA FLOWER EXTRACT | / | Technical requirements have not been made public | 2024/2/22 | Shenzhen Hujia Technology Co., Ltd. | ||
| 131 | Bis-1,4(Triethoxysilylpropylcarbamoyl Poly(Diglycol Adipate) Propylamino) Anthraquinone | / | Technical requirements have not been made public | 2024/2/20 | Intercos S.p.A. | ||
| 130 | Nicotinamide Mononucleotide | / | Technical requirements have not been made public | 2024/2/2 | Bloomage Biotechnology Co., Ltd. | ||
| 129 | Bis-Hydroxyethyl PPG/PEG-7/ PEG-4 Dicyanomethylthiophene Azotoluidine | / | Technical requirements have not been made public | 2024/1/25 | Intercos S.p.A. | ||
| 128 | SALVIA PLEBEIA EXTRACT | / | Technical requirements have not been made public | 2024/1/23 | Yunnan Botanee Biotechnology Group Co., Ltd | ||
| 127 | ERIGERON BREVISCAPUS Extract | / | Technical requirements have not been made public | 2024/1/23 | Yunnan Botanee Biotechnology Group Co., Ltd | ||
| 126 | CARYODENDRON ORINOCENSE SEED OIL | / | Technical requirements have not been made public | 2024/1/23 | Sethic (Guangzhou) Technology R&D Co., Ltd. | ||
| 125 | Bis-(Isostearoyl/Oleoyl Isopropyl) Dimonium Methosulfate | / | Technical requirements have not been made public | 2024/1/16 | Evonik Operations GmbH | ||
| 124 | Polyglyceryl-3 Stearate/Sebacate Crosspolymer | / | Technical requirements have not been made public | 2024/1/16 | Evonik Operations GmbH | ||
| 123 | Fucosyllactose | / | Technical requirements have not been made public | 2024/1/16 | Bloomage Biotechnology Co., Ltd. | ||
| 122 | β-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide | / | Technical requirements have not been made public | 2024/1/16 | Shenzhen Winkey Technology Co., Ltd | ||
| 121 | Nicotinamide Mononucleotide | / | Technical requirements have not been made public | 2024/1/16 | Shenzhen Winkey Technology Co., Ltd | ||
| 120 | Hydroxytyrosol | / | Technical requirements have not been made public | 2024/1/12 | Hangzhou Viablife Biotechnology Co., Ltd. | ||
| 119 | OPLOPANAX ELATUS Adventitious Root Extract | / | Technical requirements have not been made public | 2024/1/11 | Guangdong Longsee Medical Technology Co., Ltd. | ||
| 118 | Pyridoxine Tris-Hexyldecanoate | / | Technical requirements have not been made public | 2024/1/4 | Shanghai Keqin Technology Co., Ltd. | ||
| 117 | Kluyveromyces Lactis/Ganoderma Sinensis Ferment Filtrate | / | Technical requirements have not been made public | 2023/12/28 | Guangzhou Huanya Cosmetics Technology Co., Ltd. | ||
| 116 | Fucoxanthin | / | Technical requirements have not been made public | 2023/12/27 | Zhejiang Haitide Biotechnology Co., Ltd. | ||
| 115 | β-Nicotinamide Mononucleotide | / | Technical requirements have not been made public | 2023/12/26 | Guangzhou Futide Biotechnology Co., Ltd. | ||
| 114 | Lactobacillus Plantarum/Crithmum Maritimum Ferment Filtrate | / | Technical requirements have not been made public | 2023/12/21 | Guangzhou Huanya Cosmetics Technology Co., Ltd. | ||
| 113 | Polycitronelleth-11 | / | Technical requirements have not been made public | 2023/12/19 | P2 Science, Inc. | ||
| 112 | Sea cucumber peptide | / | Technical requirements have not been made public | 2023/12/18 | Xi'an HP Biotechnology Co., Ltd. | ||
| 111 | Cellulose Olivate | / | Technical requirements have not been made public | 2023/12/15 | Prosen Plant Technology (Suzhou) Co., Ltd. | ||
| 110 | Sodium Lauroyl Methyl Isethionate | / | Technical requirements have not been made public | 2023/12/14 | Guangzhou Tianci High-tech Materials Co., Ltd. | ||
| 109 | Gynura Procumbens Leaf/Stem Extract | / | Technical requirements have not been made public | 2023/12/14 | Guangdong Perfect Life and Health Technology Research Institute Co., Ltd. | ||
| 108 | Candida Bombicola/Glucose/Coconut Oil/Prinsepia Utilis Oil Ferment | / | Technical requirements have not been made public | 2023/12/11 | Yunnan Botanee Group | ||
| 107 | Candida Bombicola/Glucose/Prinsepia Utilis Oil Ferment | / | Technical requirements have not been made public | 2023/12/11 | Yunnan Botanee Group | ||
| 106 | α-Dextran Hydroxypropyltrimonium Chloride | / | Technical requirements have not been made public | 2023/12/7 | International Flavors (China) Co., Ltd. | ||
| 105 | Pyrroquinoline Quinone Disodium (PQQ) Salt | / | Technical requirements have not been made public | 2023/12/4 | Hunan Shuiyang Biotechnology Co., Ltd. | ||
| 104 | Sodium colanate | / | Skin protectant, moisturizer | All kinds of cosmetics, except products that may pose a risk of inhalation exposure | Bath products, hair care products (shampoo / hair styling products / conditioner): ≤100% Body lotion: ≤7.6% Facial creams: ≤38% Hand cream: ≤27% Makeup products (foundation / makeup remover / eye shadow / mascara / eyeliner): ≤100% Non-spray deodorant:≤40% Sunscreen: ≤3.3% | 2023/11/29 | PAM²L Biotechnologies |
| 103 | BAKUCHIOL | 10309-37-2 | Skin protectant, emollient, antioxidant | All kinds of cosmetics applicable for any skin | 0.5554%-3.1992% | 2023/11/28 | Yunnan Hengjin Pharmaceutical Co., Ltd. |
| 102 | Butyl Methacrylate/HEMA/Methacryloxyethyl Phosphorylcholine Copolymer | / | Skin protectant, moisturizer | All kinds of cosmetics, except spray products | ≤3% | 2023/11/23 | OLI |
| 101 | Silicone Quaternium-16/Glycidoxy Dimethicone Crosspolymer | 853411-22-0 | Hair styling agent, hair conditioner | Hair styling, shampoo, hair conditioner, hair mask, hair dyeing products (non-inhalable preparations) | 0.1-2% | 2023/11/21 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 100 | Bis-Polycitronellyl Azelate | 2810894-79-0 | Hair conditioner, moisturizer | All kinds of skin-care products, except spray products | 50% | 2023/11/21 | P2 Science, Inc. |
| 99 | Bis-Polycitronellyl Succinate | 2810894-78-9 | Hair conditioner, moisturizer | All kinds of skin-care products, except spray products | 50% | 2023/11/21 | P2 Science, Inc. |
| 98 | Isomaltooligosaccharide | / | moisturizer | All kinds of skin-care products, except spray products | ≤60% | 2023/11/16 | Sethic (Guangzhou) Technology R&D Co., Ltd. |
| 97 | PHOSPHATIDYLSERINE | 84776-79-4 | Skin protectant, hair conditioner, emulsion stabilizer, emulsifier | All kinds of cosmetics, except aerosol products and products in the form of loose powders | 5% | 2023/11/14 | Ascend |
| 96 | Bakuchiol | 10309-37-2 | Skin protectant, skin sensory modifier, moisturizer, antioxidant | Cosmetics applicable to face, eyes, hands, neck and lips | 2% | 2023/11/13 | Sytheon Corporation |
| 95 | SORBETH-230 TETRAOLEATE | 63089-86-1 | Thickener, emulsifier | All kinds of cosmetics, except spray products | 10% | 2023/11/7 | Applechem, Inc. |
| 94 | AMINOLEVULINIC ACID HCl | 5451-09-2 | Hair conditioner, moisturizer, antioxidant, exfoliating agent | Shampoo, hair conditioner, facial cleansing products, bath products, and whole-body skin care products, except aerosol products, products in the form of loose powders, lip products and oral hygiene products | Leave-on body care products: ≤0.008% Leave-on skin care products: ≤0.039% Rinse-off body care products: ≤0.321% Rinse-off hair care products: ≤0.574% | 2023/11/7 | Bloomage Biotechnology Co., Ltd. |
| 93 | 3,3,5-TRIMETHYLCYCLOHEXYL SUCCINATE DIMETHYLAMIDE | 1449076-27-0 | Skin protectant, antioxidant | All kinds of skin-care products, except aerosol products and products in the form of loose powders | Leave-on body care products:<7.67% Leave-on skin care products:<38.96% Rinse-off body care products:<100.00% Rinse-off hair care products:<100.00% Sunscreens:<3.33% | 2023/11/3 | Proya Cosmetics Co. Ltd |
| 92 | Nicotinamide Mononucleotide/β-Nicotinamide Mononucleotide | 1094-61-7 | Anti-wrinkle agent,skin protectant, moisturizer, antioxidant | All kinds of skin-care products, except spray products | ≤3% | 2023/11/1 | Harbin Voolga Technology Co., Ltd. |
| 91 | Hydroxy-α-sanshool | 83883-10-7 | Skin protectant, antioxidant | All kinds of cosmetics, except aerosol products and products in the form of loose powders | Leave-on body care products:<0.721% Leave-on skin care products:<3.662% Rinse-off body care products:<30.208% Rinse-off hair care products:<14.1% Sunscreens:<0.313% | 2023/10/30 | Sichuan Shengjia Technology Co., Ltd. |
| 90 | BLACK GINSENG EXTRACT | / | Skin protectant, anti-wrinkle agent | All kinds of cosmetics, except spray and aerosol products | 2% | 2023/10/25 | Hunan S'YOUNG Biotechnology Co., Ltd. |
| 89 | Vitamin K2(35) | 2124-57-4 | Skin protectant, antioxidant | All kinds of cosmetics, except spray products and products in the form of loose powders | Facial cream: 0.389% Hand cream: 0.277% Body lotion: 0.076% Other products: 1% (recommended) | 2023/10/25 | Ascend |
| 88 | Acetyl Octapeptide-1 | 1800022-08-5 | Skin protectant | All kinds of cosmetics, except lip products, oral hygiene products and spray products | ≤0.05% | 2023/10/18 | BIOINPE |
| 87 | ASINI CORII COLLA POWDER | / | Anti-wrinkle agent, moisturizer | All kinds of cosmetics | 62% | 2023/10/17 | Dong-E-E-Jiao Co., Ltd. |
| 86 | Bakuchiol | 10309-37-2 | Skin protectant, skin sensory modifier, humectant, antioxidant | Cosmetics applicable to eyes, hands, neck and lips | 2% | 2023/10/13 | Sytheon Corporation |
| 85 | Cestrum Latifolium Leaf Extract | 1151559-82-8 | Skin protectant | All kinds of skin-care products, excluding spray products | ≤2% | 2023/10/12 | BASF |
| 84 | Urolithin A | 1143-70-0 | Anti-wrinkle agent | All kinds of skin-care products, except spray products | 0.5%-1% | 2023/10/12 | Amazentis SA |
| 83 | SCHIZOPHYLLUM COMMUNE MYCELIUM FERMENT EXTRACT | / | Skin protectant, moisturizer | All kinds of cosmetics, except spray products | Shower gel, hair care products (shampoo / hair styling products / conditioner), facial creams, makeup products (foundation / makeup remover / eye shadow / mascara / eyeliner), non-spray deodorant: ≤100% Hand cream: ≤83% Body lotion: ≤23% Sunscreen: ≤10% | 2023/9/27 | Zhejiang Gllion Biotechnology Co., Ltd. |
| 82 | Microcitrus australasica (F. Muell.) Swingle extract | / | Skin protectant, moisturizer | This ingredient is only used for addition to cosmetics, except spray products. The recommended addition amount in cosmetics is 0.039-5.0%. Try to add it at the final stage of cosmetic production. The addition temperature should not exceed 40°C. | 100% | 2023/9/25 | Guangdong Marubi Biotechnology Co., Ltd. |
| 81 | Cell Culture of Saussurea Involucrate | / | Moisturizer, antioxidant | All kinds of cosmetics, excluding spray products | ≤5.0% | 2023/9/25 | Acelbio (Chongqing) Biotechnology Co., Ltd. |
| 80 | Bifidobacterium/Lactobacillus/Soybean Seed Extract Ferment Filtrate | / | Skin protectant, oil control agent, moisturizer, exfoliating agent | All kinds of cosmetics, excluding spray products | ≤5.0% | 2023/9/21 | Guangzhou Yatsen E-Commerce Co., Ltd. |
| 79 | Nicotinamide Mononucleotide | 1094-61-7 | Moisturizer | All kinds of cosmetics, excluding spray and lip products | ≤3.3% | 2023/8/16 | Jiangxi Haiwen Biotechnology Co., Ltd. |
| 78 | Pyrroloquinoline quinone disodium （PQQ）salt | 122628-50-6 | Skin protectant | All kinds of cosmetics, excluding spray products | ≤0.08% | 2023/8/2 | Hunan S'YOUNG Biotechnology Co., Ltd. |
| 77 | LUDWIGIA ADSCENDENS EXTRACT | / | Skin protectant, moisturizer | All kinds of cosmetics, excluding spray and lip products | ≤3.3% | 2023/7/26 | Yunnan Botanee Group |
| 76 | Pandanus Amaryllifolius Leaf Extrac | / | Moisturizer | All kinds of skin-applicable cosmetics | Leave-on body products: ≤ 8%; Other products: ≤ 30% | 2023/7/25 | Guangdong Bawei Biotechnology Co., Ltd. |
| 75 | CELLULOSE ACETATE PROPIONATE | 9004-39-1 | Film-former | All kinds of cosmetics | ≤50% | 2023/7/11 | Eastman Chemical Company |
| 74 | PARIS FARGESII RHIZOME EXTRACT | / | Skin protectant | All kinds of cosmetics,excluding spray and aerosol products | Rinse-off products: 2.5%; Leave-on products: 1.12% | 2023/7/11 | Yunnan Baiyao Group Shanghai Technology Co., Ltd. |
| 73 | Galactomannan | / | Moisturizer | All kinds of cosmetics, excluding spray products | 5% | 2023/7/10 | Beijing Guarrun Technology Co., Ltd. |
| 72 | Tripeptide-105 | / | Skin protectant | Products in the form of balms, creams and emulsions; not added to products in the form of aerosols or loose powders | ≤0.5% | 2023/6/20 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 71 | Cyclopeptide-161 | / | Skin protectant and moisturizer | All kinds of skin-applicable cosmetics, excluding spray products | ≤3.33% | 2023/6/20 | Zhejiang Peptites Biotech Co., Ltd. |
| 70 | Ethyl Methicone | 63148-54-9 | Emollient | All kinds of cosmetics | ≤ 5.0%, recommended concentration in cosmetics: 1.0-5.0%. | 2023/6/14 | Siltech Corporation |
| 69 | ILEX LATIFOLIA LEAF EXTRACT | / | Technical requirements have not been made public | 2023/5/30 | Guangzhou Hanfang Medical Biotechnology Co., Ltd. | ||
| 68 | TEA-Acrylate/TEA-Acryloyldimethyl taurate Copolymer | / | Film-former, adhesive, and thickener | All kinds of cosmetics with a pH below 5.0 | Rinse-off products: 0.1-10%; Leave-on products: 0.1-10% | 2023/5/22 | Guangzhou Bafeorii Chemical Co., Ltd. |
| 67 | TOCOPHERYL RETINOATE | 40516-49-2 | Face cream / face lotion / face essence: 11.68%; Lotion: 6%; Facial mask: 6.25%; Body lotion: 2.3%. | All kinds of cosmetics, excluding spray products | Face cream / face lotion / face essence: 11.68%; Lotion: 6%; Facial mask: 6.25%; Body lotion: 2.3%. According to the compatibility of ingredients, the suggested addition amount: 0.01-5%. | 2023/5/18 | Shanghai Keqin Technology Co., Ltd. |
| 66 | FUSCOPORIA OBLIQUA/ BETULA ALBA JUICE FERMENT | / | Moisturizer and antioxidant | Rinse-off products, leave-on products (for body, face, eye, lip), essence, foundation, hand cream, body sunscreen | Rinse-off products: ≤100%; Leave-on products (for body): ≤ 7.67%; Essence: ≤ 83.33%; Foundation: ≤ 100%; Leave-on products (for face): ≤ 38.96%; Leave-on products (for eye): ≤ 100%; Leave-on products (for lip): ≤ 100%; Hand cream: ≤ 17.64%; Body sunscreen: ≤ 3.33% | 2023/5/17 | Yangshengtang (Anji) Cosmetics Co., Ltd. |
| 65 | MESEMBRYANTHEMUM CRYSTALLINUM CALLUS EXTRACT | / | Skin protectant and moisturizer | All kinds of cosmetics | ≤1% | 2023/5/16 | Baiyuet Biotechnology (Shanghai) Co., Ltd. |
| 64 | ACETYL CARNOSINE | 56353-15-2 | Skin protectant and moisturizer | All kinds of cosmetics, excluding lip products, oral hygiene products and spray products | ≤1% | 2023/5/16 | Shenzhen Readline Biotechnology Co., Ltd. |
| 63 | Hexyl/Succinyl Dimethicone Crosspolymer | 2486020-17-9 | Film-former, skin sensory modifier, thickener, emulsion stabilizer | Skin care, make-up, sunscreen cosmetics (non-inhalable preparations) | 0.5-25% | 2023/5/10 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 62 | HYDROXYMETHOXYPHENYL DECANONE | 27113-22-0 | Antioxidant | All kinds of cosmetics, excluding spray products | 0.002-0.02% (varies according to different cosmetic categories, but excluding spray products) | 2023/5/5 | Symrise Flavors and Fragrances (Nantong) Co., Ltd. |
| 61 | GYNURA PROCUMBENS EXTRACT | / | Skin protectant, antioxidant | All kinds of cosmetics, excluding spray products | ≤25% | 2023/5/5 | Wenzhou Gumu Biotechnology Co., Ltd. |
| 60 | Alpha-Glucan Polysaccharide | 9051-95-0 | Film-former, abrasive agent, slip agent, adhesive, absorbent, and exfoliator | Bath soaps; body and hand care products; cleansing products (cold creams, cleansing milk and solution, wipes); face creams; face and neck care products; liquid foundations; perfumes; lipsticks; primers; make-up; mascaras; body lotions; nail polishes; night skin care products; cream masks (clay masks); personal cleansing products; sunscreen products; hair care products; deodorants, etc. | ＜90% | 2023/4/7 | International Flavors & Fragrances Inc. |
| 59 | CARBOXYDECYL TRISILOXANE | 63672-06-0 | Skin sensory modifier and emulsifier | All kinds of cosmetics | ≤2% | 2023/4/6 | Shiseido Co., Ltd. |
| 58 | Mu-conotoxin CnIIIC | 936616-33-0 | Skin protectant | Products in the form of balms, creams and emulsions; not added to products in the form of aerosols or loose powders | ≤0.0025% | 2023/4/4 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 57 | Acetyl Hexapeptide-95 Amide | / | Skin protectant | Products in the form of balms, creams and emulsions; not added to products in the form of aerosols or loose powders | ≤0.05% | 2023/3/14 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 56 | Caffeoyl Hexapeptide-9 | / | Skin protectant | Products in the form of balms, creams and emulsions; not added to products in the form of aerosols or loose powders | ≤0.03% | 2023/3/14 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 55 | Asivatrep | 1005168-10-4 | Skin protectant | All kinds of skin-applicable cosmetics, excluding spray products | Products for torso: 0.08% Facial Products: 0.4% Hand products: 0.3% | 2023/3/3 | AMOREPACIFIC CORPORATION |
| 54 | Hydrogenated Farnesene | 3891-98-3 | Moisturizer, solvent | Leave-on and rinse-off cosmetics | ≤40% (16% for sunscreen products) | 2023/2/27 | Aprinnova, LLC |
| 53 | Nicotinamide Mononucleotide | 1094-61-7 | Skin protectant, moisturize | All types of skin cosmetics except sprays, powders and other cosmetics that may be inhaled | Body resident products ≤3% Other products ≤10% | 2023/2/8 | Uthever Technology (Shanghai) Co., Ltd. |
| 52 | Hydrolyzed Alpha-Glucan Polysaccharide | 9051-95-0 | Film-former, adhesive, moisturizer, emulsion stabilizer, emollient | Bath soap; body and hand care products; cleansing products (cold creams, cleansing lotions, liquids, wipes); facial creams; face and neck care products; foundation; perfume; lipstick; primer; make-up; mascara; Body lotions; nail polishes and polishes; night-time skin care products; cream masks (face masks); personal cleansing products; sun protection products; hair care products; deodorants, etc. | 90% | 2023/2/7 | International Flavors & Fragrances Inc. |
| 51 | Dihydro Avenanthramide D Potassium | 2768430-39-1 | Skin protectant | All kinds of cosmetics | Rinse-off products: 10%; Leave-on products: 3% | 2023/1/6 | Fuzhou Bioanti Biotechnology Co., Ltd. |
| 50 | Azelamidopropyl Dimethyl Amine | 1272659-40-1 | Skin protectant | All kinds of skin-applicable cosmetics | 2% | 2023/1/4 | CORUM Inc. |
| 49 | Donkey Oil | / | Moisturizer | All kinds of skin-applicable cosmetics | Products for torso: 8% Facial Products: 41% Hand products: 30% Lip products: no limit | 2023/1/4 | Dong-E-E-Jiao Co., Ltd. |
| 48 | Nicotinoyl Tetrapeptide-30 | / | Skin protectant | All kinds of cosmetics applicable for any skin | ≤0.1% | 2022/12/29 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 47 | Swiftlet nest peptide | / | Skin protectant, antioxidant | All kinds of cosmetics applicable for any skin | ≤0.3% | 2022/12/8 | Xiamen Yanzhiwu Silk Nong Food Co., Ltd. |
| 46 | Donkey Milk Powder | / | Astringent | All kinds of cosmetics applicable for any skin | 46% | 2022/12/8 | Dong-E-E-Jiao Co., Ltd. |
| 45 | Euphausia Superba Oil | / | Moisturizer | All kinds of cosmetics | ≤18.5% | 2022/11/4 | Zhongguan Biotechnology (Hunchun) Co., Ltd. |
| 44 | Cordyceps cicadae mycelium extract | / | Skin protectant, moisturizer, antioxidant | All kinds of cosmetics applicable for any skin | Recommended concentration: 1-10%, theoretical experience value | 2022/11/4 | Shanghai Grape King Co., Ltd. |
| 43 | Perfluorobutylethl Stearyl Dimethicone | 915223-67-5 | Hair styling agent, moisturizer, dispersant | All kinds of cosmetics | ≤2% | 2022/10/28 | Elkem Silicones (Shanghai) Co., Ltd. |
| 42 | Hibiscus taiwanensis root/stem extract | / | Skin Protectant, antioxidant | Rinse-off and leave-on cosmetics | ≤2% | 2022/10/17 | Juwenlee (Fujian) Cosmetics Co., Ltd. |
| 41 | Sodium Hydrolyzed Potato Starch Dodecenylsuccinate | 1218992-20-1 | Foaming agent | Rinse-off cosmetics | ≤10% | 2022/10/13 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 40 | Laurol/Myristoyl Methyl Glucamide | 287735-50-6 | Softener, foaming agent, skin sensory modifier, hair conditioner, cleanser | Rinse-off cosmetics | ≤7% | 2022/10/9 | Clariant International Ltd. |
| 39 | Bis-Diisopropanolamino-PG-Propyl Dimethicone/Bis-Isobutyl PEG-14 Copolymer | 1253692-80-6 | Hair conditioner | Shampoo, hair conditioner, hair dyeing products, hair mask products | There is no safety-based usage limit requirements. However, according to the application and formula test results, notifer’s recommended concentration is 0.1-6% by weight in the formula of shampoo, hair conditioner, hair dyeing products, and hair mask products. | 2022/9/20 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 38 | Palmtoyl Dipeptide-18 | 1206591-87-8 | Thickener | All kinds of cosmetics | ≤2% | 2022/9/15 | Nissan Chemical Corporation |
| 37 | Silicone Quaternium-26 | 1551351-87-1 | Hair conditioner | Shampoo, hair conditioner, hair mask, hair oil and other hair care products | ≤10% | 2022/9/15 | Momentive (Shanghai) Trading Co., Ltd. |
| 36 | Acetobacter/Lactobacillus/Saccharomyces/Camellia Sinensis Leaf Extract/Sucrose Ferment Filtrate | / | Skin protectant | All kinds of skin cosmetics | ≤5% | 2022/9/13 | Sethic (Guangzhou) Technology R&D Co., Ltd. |
| 35 | Saccharomyces / Pearl Ferment Lysate Filtrate | / | Skin protectant, moisturizer and antioxidant | All kinds of cosmetics | 1) For facial leave-on cosmetics: Essence: ≤8% Cream: ≤7% Lotion: ≤4% Sunblock: ≤22% Foundation (liquid): ≤25% Foundation (powder): ≤41% Other products: ≤1.9% 2) For body leave-on cosmetics: Body cream and lotion: ≤0.7% Other products: ≤0.3% 3) Hand cream: ≤1.7% 4) Eye leave-on cosmetics: ≤9% 5) Lip leave-on cosmetics: ≤100% 6) Facial rinse-off cosmetics: ≤100% | 2022/9/13 | Zhejiang Osm Group Deqing Bio-tech Co., Ltd. |
| 34 | Polyactic Acid | 9051-89-2 | Film former, exfoliator, emulsion stabilizer, emulsifier | All kinds of cosmetics | ≤10% | 2022/9/5 | LX Hausys，Ltd. |
| 33 | Bakuchiol | 10309-37-2 | Skin protectant, skin sensory modifier, moisturizer and antioxidant | All kinds of facial cosmetics | 2% | 2022/8/26 | Sytheon Corporation |
| 32 | Acetylneuraminic Acid | 131-48-6 | Anti-wrinkle agent, skin protectant, moisturizer, antioxidant | Whole body skin | ≤2.0% | 2022/8/19 | Bloomage Biotechnology Co., Ltd. |
| 31 | Polyurethane-48 | 1346107-02-5 | Film former | Leave-on cosmetics | 30% | 2022/8/19 | Covestro Deutschland AG |
| 30 | Polyurethane-34 | 67815-81-0 | Film former | Leave-on cosmetics | 32% | 2022/8/19 | Covestro Deutschland AG |
| 29 | CYCLOHEXYLGLYCERIN | 10305-41-6 | Moisturizer | All kinds of skin care, hair care and makeup products | ≤5.0% | 2022/8/18 | Adeka Corporation |
| 28 | TMP Lauryl Dimethicone | 1961223-88-0 | Emulsion stabilizer | All kinds of cosmetics | ≤5.0%, recommended concentration in cosmetics: 1.0-5.0%, 3.0-5.0% is better | 2022/8/2 | Siltech Corporation |
| 27 | PIPERIDINEPROPIONIC ACID | 26371-07-3 | Moisturizer | All kinds of cosmetics | ≤3.0% | 2022/7/28 | Shiseido Co., Ltd. |
| 26 | Hydroxyethyl Imidazolidinone | 3699-54-5 | Moisturizer | All kinds of cosmetics | ≤1.5% | 2022/7/28 | Shiseido Co., Ltd. |
| 25 | Dimethicone/Bis-Isobutyl PPG-20 Crosspolymer | 1043538-34-6 | Skin sensory modifier and thickener | Skin care, makeup and sunscreen cosmetics | 0.17-11% | 2022/7/28 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 24 | Silicone Quaternium-20 | 280569-78-0 | Hair conditioner | All kinds of hair cosmetics | ≤3.0%, recommended concentration in cosmetics: 0.5～3.0% | 2022/7/20 | Siltech Corporation |
| 23 | chlorotrifluoropropene | 102687-65-0 | Solvent, cooling agent | 1. Leave-on products: skin cosmetics, hair cosmetics 2. Rinse-off products: skin cosmetics, hair cosmetics | ≤90% | 2022/7/18 | Honeywell Trading (Shanghai) Co., Ltd. |
| 22 | Hydrolyzed calcium hyaluronate | / | Skin protectant and moisturizer | All kinds of cosmetics | ≤2.0% | 2022/7/12 | Bloomage Biotechnology Co., Ltd. |
| 21 | lard | 61789-99-9 | Skin protectant, emollient, moisturizer, solvent, and sealing agent | Oil-phase matrix cosmetic ingredients, and can be widely used in cream, lotion, cleaning, sunscreen, makeup and other cosmetics. | ≤95% | 2022/7/6 | Sichuan Luming Hill Ecological Agriculture Technology Co., Ltd. |
| 20 | Amidinobenzyl Benzylsulfonyl D-Seryl Homophenylalaninamide Acetate | 1393815-16-1 | Skin protectant and moisturizer | All kinds of cosmetics applicable for any skin, including rinse-off and leave-on types | 0.001% | 2022/7/5 | DSM Vitamins (Shanghai) Co., Ltd. |
| 19 | Nicotinamide Mononucleotide | 1094-61-7 | Skin protectant, moisturizer, and antioxidant | All kinds of skin-applicable cosmetics | ≤3% | 2022/6/29 | Yuyao Lifespan Health Technology Co., Ltd. |
| 18 | Oligopeptide-215 | / | Skin protectant | All kinds of skin-applicable cosmetics | ≤3.0% | 2022/6/14 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 17 | Acetylneuraminic Acid | 131-48-6 | Anti-wrinkle agent, antioxidant, skin protectant, and moisturizer | Whole-body skin | ≤2.0% | 2022/5/31 | Wuhan Zhongke Optics Valley Green Biotechnology Co., Ltd. |
| 16 | Dendrobium Officinale Protocorm | / | Anti-wrinkle agent, moisturizer | All kinds of cosmetics | ≤4.0% | 2022/5/18 | Dalian Practical Biotechnology Co., Ltd. |
| 15 | β-Nicotinamide Mononucleotide | 1094-61-7 | Anti-wrinkle agent, skin protectant, antioxidant | All kinds of skin-applicable cosmetics | ＜3% | 2022/4/29 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 14 | Zinc hydrolyzed hyaluronate | / | Skin protectant, moisturizer | All kinds of cosmetics | ≤1.0% (as Zinc) | 2022/4/20 | Bloomage Biotechnology Co., Ltd. |
| 13 | β-Nicotinamide Mononucleotide | 1094-61-7 | Skin protectant, moisturizer | All kinds of skin-applicable cosmetics | ≤10% | 2022/3/29 | Kangying Rubyberries (Zhongshan) Biotechnology Co., Ltd. |
| 12 | Chenopodium formosanum Extract | / | Skin protectant | All kinds of cosmetics | ≤0.7% | 2022/3/7 | Baiyuet Biotechnology (Shanghai) Co., Ltd. |
| 11 | Bis-Cetearyl Amodimethicone | 1126942-72-0 | Hair conditioner | Shampoo, hair conditioner, hair treatment and other hair care products | ≤10% | 2022/2/23 | Momentive (Shanghai) Trading Co., Ltd. |
| 10 | Sodium Acryloydimethyltaurate/VP Crosspolymer | 1176663-96-9 | Thickener | All kinds of cosmetics | Rinse-off cosmetics: 5%; Leave-on cosmetics: 2.5% | 2022/2/16 | Clariant International Ltd. |
| 9 | Polymethylsilsesquioxane/Trimethylsiloxysilicate | 1402155-47-8 | Film Former | All kinds of cosmetics | ≤30% | 2022/1/25 | Grant Industries, Inc |
| 8 | Nicotinamide Mononucleotide | 1094-61-7 | Skin protectant, moisturizer, antioxidant | All types of cosmetics, except lip products, oral hygiene products and spray products | ≤3% | 2022/1/24 | Yuyao Lifespan Health Technology Co., Ltd. |
| 7 | Cetyl Diglyceryl Tris(Trimethylsiloxy)silylethyl Dimethicone | 1466529-58-7 | Emulsifying agent | All kinds of cosmetics | 2%-8% | 2022/1/17 | Dow Chemical (Zhang Jiagang) Investment Co., Ltd. |
| 6 | Sodium Lauroyl Methyl Isethionate | 928663-45-0 | Cleansing agent | Shampoo, bath products, facial cleansing products and other cleansing cosmetics, excluding eye products) | ≤11% | 2021/12/8 | Innospec (Beijing) Inc. |
| 5 | Tetrafluoropropene | 29118-24-9 | Propellant | 1. Leave-on products: skin cosmetics, hair care cosmetics 2. Rinse-off products: skin cosmetics, hair care cosmetics | ≤90% | 2021/12/2 | Honeywell International Inc. |
| 4 | Tissue Culture of Saussurea Involucrata | / | Antioxidants | All kinds of cosmetics | ≤4% | 2021/8/13 | Dalian Practical Biotechnology Co., Ltd. |
| 3 | Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide | / | Skin protectant | 1. Rinse-off products: cleansing products and massage products 2. Leave-on products: toner, lotion, mask, etc. 3. Make-up: foundation | 0.00001%-1.0% | 2021/8/13 | Shenzhen Winkey Pharmaceutical R&D Co., Ltd. |
| 2 | Lauroyl Alanine | 52558-74-4 | Cleansing agent | All kinds of cosmetics | ≤20% | 2021/6/28 | Suzhou Weimei Biotechnology Co., Ltd. |
| 1 | Acetylneuraminic Acid | 131-48-6 | Moisturizer | Whole-body skin | ≤2% | 2021/6/28 | Wuhan Zhongke Optics Valley Green Biotechnology Co.,Ltd. |
| Notes: The detailed technical requirements for part of newly notified NCIs have not been made public. The English translations above are merely literal translations based on these NCIs' Chinese names, which may differ from the INCI names provided by notifiers. | |||||||
